This meeting will focus on current research at the intersection of genetics, computer science, statistics, and related fields in gathering and analyzing SNP and haplotype data and applying it to problems in medicine and basic research. Population genetics allows more refined understanding of the demographic history of our species, association analysis provides insights regarding the functional and molecular underpinnings of diseases and traits, while clinical applications suggest genetics as a trailblazer into personalized medicine. The complex bioinformatic questions arising range from inferring more nuanced statistical models of genetic information to algorithms that overcome the complexity challenges of analyzing millions of SNPs across millions of individuals, to systems level challenges of handling such Big Data repositories of genotypes and phenotypes.
Original research papers (including significant work-in-progress) or state-of-the-art surveys are solicited in all aspects of SNP analysis and genetics, including, but not limited to:
- Association analysis pipelines, imputation, phasing and meta-analysis
- Rare variants analyses and burden tests
- Risk/phenotype prediction models and heritability analysis
- Analysis of molecular and ‘omics phenotypes (e.g., gene expression and other epigenetic markers)
- Complex associations including mixed models, epistasis, normalization
- Structured phenotypes: multiple/serial/intermediate phenotypes and pleiotropy
- Inference of population structure and demographic history
- Models for mutation, recombination, selection, and conservation
- Relatedness and identity-by-descent
- Structural variation
- Ancient demography
We solicit contributions in four different categories as follows:
Highlights Track Abstracts
1-2 pages describing computational aspects of work that has been published in a journal after December 1, 2018, or papers that are in press at the time of submission and are already linked on the journal website. This track is joint with the main RECOMB conference.
Short Talks / Posters / Lightning Poster Talks
Regular 1-page abstracts describing original work, including software applications. These will be considered for short presentations as well as for posters. Lightning poster talks will be encouraged to acquaint the audience with work presented in a poster.
Abstracts should be single (1-2 for highlight) single-spaced US letter or A4 pages with at most a 6.5×9″ text area in at least 11 point font. Title and authors, corresponding author’s email address, figures, and tables all included. An optional link to a full-details version on bioRxiv is allowed contingent on commitment for maintaining static content of such a version between submission and the conference. Abstracts must be submitted electronically in PDF format via the EasyChair system through the RECOMB 2019 conference, by selecting the genetics satellite from the menu.
Original abstracts submitted for review should represent original, previously unpublished work. At the time of submission to the workshop, and for the entire review period, the work should not be under review by any other conference or scientific journal.
The submission system will be open until February 1st, 2019. Authors will be notified of acceptance or rejection by email on or before February 21th, 2019. An author of each accepted abstract is expected to attend the workshop and present the paper; otherwise, alternative arrangements should be made to have the paper presented.